更新時間:2024-11-17
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廠商性質(zhì):經(jīng)銷商
生產(chǎn)地址:
1-Azakenpaullone 676596-65-9
1-Azakenpaullone
分子式:C15 H10 Br N3 O 分子量:328.16
產(chǎn)品描述
1-Azakenpaullone是一種細胞滲透性的、有效的、ATP競爭性的GSK-3β抑制劑,IC50為18nM
靶點
GSK-3β
IC50
18 nM
生物活性
A Kenpaullone analog that acts as a potent and ATP-competitive inhibitor of GSK-3β (IC50 = 18 nM), and displays ~100-200 fold greater selectivity over Cdk1/B and Cdk5/p25 (IC50 = 2 µM and 4.2 µM, respectively). Also available as a 10 mM solution in DMSO
溶解性
DMSO (~ 100 mg/ml)
穩(wěn)定性
2年 -20°C粉狀,6月-80°C溶于DMSO